Oncolytic Adenoviruses in Gastrointestinal Cancers
نویسندگان
چکیده
منابع مشابه
Oncolytic Adenoviruses in Gastrointestinal Cancers
Gastrointestinal malignancies are challenging cancers with considerable economic and societal impacts on health care systems worldwide. While advances in surgical approaches have provided benefits to a proportion of patients, only modest improvements have been attained in the treatment of patients with advanced disease, resulting in limited improvement in survival rates in these patients. Oncol...
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The therapeutic use of viruses against cancer has been revived during the last two decades. Oncolytic viruses replicate and spread inside tumors, amplifying their cytotoxicity and simultaneously reversing the tumor immune suppression. Among different viruses, recombinant adenoviruses designed to replicate selectively in tumor cells have been clinically tested by intratumoral or systemic adminis...
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ژورنال
عنوان ژورنال: Biomedicines
سال: 2018
ISSN: 2227-9059
DOI: 10.3390/biomedicines6010033